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Vaccine Innovation

Vaccine Innovation

We collaborate with the global public health community on the development of optimized vaccines with target product profiles relevant to the low income countries.

Hilleman Laboratories aspires to become a ‘Center of Excellence’ for the effective and affordable development, delivery and distribution of vaccines to fight the diseases prevalent in the under developed regions of the world. Our translational research focuses on creating safe, low-cost vaccines, that are highly effective and can be easily incorporated into the child immunization programs.

Focus areas in vaccine project research and development

Innovate

Access

Affordability

Availability

Thermostability

The vaccine should be heat-stable with a stability profile that meets the needs of the developing countries.

Ease-of-use

The vaccine should be easy to administer in field settings and limit biological waste.

Optimize

Thermostability

Packaging

Delivery

Package size

The vaccine should be packaged in a manner that is easy to transport, store, and administer.

Reduced cost of goods

The vaccine production cost by manufacturers should be affordable for use in the developing countries.

From translational biology, bioprocess, formulation and analytical research to licensing, we are involved with the early development of vaccines Phase I /II of clinical trials (proof-of-principle), project management, advocacy and fund raising, impact assessment and communication. Our vaccine research model encompasses the following:

  • Due-Diligence
  • Identify Vaccine Antigen
  • Identify Vaccine Technology
  • Optimization
  • Preclinical Development
  • Clinical Phase I / II
  • Technology Transfer for Manufacturing
  • Transformational Technology for Vaccine Development and Administration

Vaccine Development Cycle

Stage
Basic
Research
Early
Development
Late
Developement
Large Scale
Manufacturing
Marketing and
Distribution
Responsible
Academic Research Groups
Biotech & Pharma Companies
MSD Wellcome Trust Hilleman Laboratories
Multi-National Pharmaceutical Manufacturers,
Developing Country Vaccine Manufacturers(DCVM)
 
Partner Outreach & Support